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Signs of Undiagnosed Celiac Disease in Adults

Last updated: 2025/05/06 at 8:01 AM
By Precious Samson
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6 Min Read
Signs of Undiagnosed Celiac Disease in Adults
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Celiac disease is more than simply a digestive condition, and it is certainly not limited to children. Adults’ symptoms frequently manifest in subtle, systemic ways that do not immediately indicate a gluten-induced immunological reaction. As a result, many adults go years without receiving a diagnosis. Meanwhile, gluten continues to irritate the lining of their small intestine, resulting in significant consequences.

Gluten, a protein present in wheat, barley, and rye, triggers an autoimmune disorder. When a person with celiac disease consumes gluten, their immune system assaults the lining of the small intestine, affecting nutritional absorption and triggering symptoms that reach well beyond the gut. Let’s look at the most frequent and sometimes missed symptoms of undiagnosed celiac disease in adults.

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Chronic Digestive Problems That Persist Despite Treatment

Adults with untreated celiac disease may endure persistent stomach discomfort that defies reason. Bloating, cramps, diarrhea, constipation, and nausea may occur intermittently but seldom resolve completely. These symptoms are sometimes misunderstood as IBS or acid reflux. If you’ve tried reducing dairy, increasing fiber consumption, or taking over-the-counter treatments without success, celiac disease could be the underlying cause of your digestive issues.

Unrelenting Fatigue and Difficulty Thinking Clearly

Fatigue is one of the most commonly reported non-digestive symptoms among individuals with untreated celiac disease. This isn’t just normal exhaustion; it’s a constant lack of energy that interferes with regular activities. Many adults suffer “brain fog,” which can manifest as mental sluggishness, difficulty concentration, or forgetfulness. These cognitive symptoms are frequently linked to vitamin B12 and iron deficits caused by impaired nutrition absorption in the damaged gut lining.

Anemia That Won’t Improve with Iron Supplements

Iron deficiency anemia is one of the initial clinical indications of celiac disease in adults. Despite taking iron supplements, people may continue to have low hemoglobin and ferritin levels. This occurs because the small intestine is unable to absorb iron effectively when inflamed. Adults may also experience dizziness, shortness of breath with light exercise, pale complexion, and a general sense of weakness. These symptoms frequently go undiagnosed for years before celiac disease is discovered as the underlying cause.

Weight Loss or Difficulty Maintaining a Healthy Weight

Unexpected weight loss without dietary changes or sickness may indicate nutritional malabsorption caused by celiac disease. The injured gut struggles to take calories, fat, and protein from food, resulting in weight swings and muscle loss in some people. However, some individuals with celiac disease may remain overweight, particularly if inflammation and hormone abnormalities persist in addition to a high-calorie diet. Unexplained weight changes, regardless of body size, should be investigated further.

Itchy, Blistering Skin That Doesn’t Respond to Creams

Dermatitis herpetiformis, a chronic, severely itchy rash, is a lesser-known yet distinguishing feature of celiac disease. It frequently develops on the elbows, knees, buttocks, and scalp and can be misinterpreted as eczema or psoriasis. Topical treatments often do not provide relief because the underlying reason is internal gluten exposure causes the skin eruption. This rash can appear even when no stomach symptoms are present, making it an important diagnostic sign.

Mouth Ulcers, Gum Problems, and Damaged Tooth Enamel

The health of your mouth frequently mirrors the health of your stomach. Adults with undiagnosed celiac disease may experience frequent canker sores, swollen gums, and a burning feeling in the mouth or tongue. Dentists may notice enamel degradation, particularly on the inner surfaces of the teeth. These dental problems are caused by persistent vitamin and mineral shortages, particularly in calcium and B vitamins, and can occur even in people who otherwise maintain adequate oral hygiene

Infertility or Hormonal Imbalance in Both Genders

Celiac illness can potentially affect reproductive health. In women, it may cause irregular menstrual cycles, early menopause, or difficulties conceiving. Hormonal imbalances in men can cause low testosterone levels, reduced libido, and fertility issues. Because these difficulties frequently arise in the absence of other visible symptoms, they might create diagnostic delays. When there is no other reason for reproductive problems, fertility professionals frequently look for celiac disease.

Final thoughts: Recognizing the Silent Symptoms of Celiac Disease

Celiac disease typically goes unnoticed in adulthood because its symptoms are similar to those of other prevalent health issues. Chronic weariness, stomach discomfort, mood swings, skin irritation, and vitamin deficits are not coincidental—they could be signs from your body that something is wrong. Left untreated, celiac disease can cause long-term consequences, but with awareness and testing, recovery is achievable.

If you’ve been experiencing inexplicable symptoms for years, it’s worth investigating whether gluten is the cause. A diagnosis could alter your health and provide a clear route to recovery via a gluten-free diet that is carefully controlled.

TAGGED: Celiac disease
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